drug pricing
Foreign drug reference pricing rears its 'big, beautiful' head
As House Republicans work out a “big, beautiful bill” to enact President Trump’s tax cuts, the White House is urging the party to tie Medicaid payment for drugs to prices abroad. The idea is to wring some savings from the pharma industry, taking pressure off of Medicaid.
Progress was made over the weekend, according to three sources. It’s more than a mere trial balloon, but the policy is still in the early stages of development and as of last week congressional Republicans hadn’t warmed to the idea.
Moderate Republican Rep. Jeff Van Drew (N.J.) said he would consider it, but warned it would need to be done “with a scalpel and make sure that we don't affect the medical supply chain.” Conservative Republican Rep. Chip Roy (Texas) said he’d need to see the proposal before taking a firm stance, but that his inclination is to oppose “price fixing on drugs.”
The pharmaceutical industry is already warning it wouldn’t save much money and would instead benefit hospitals via the 340B drug discount program.
clinical research
NIH clinical trial center in crisis
The National Institutes of Health’s storied Clinical Center is struggling to carry out its mission of running clinical trials for the hardest-to-treat diseases amid growing disruptions from the Trump administration, Jonathan Wosen and Jason Mast report.
It’s been a fast turn of events for a facility that has long been known as the nation’s largest hospital devoted solely to medical research.
Fewer patients are being treated, and some trials are lagging months behind due to reduced staffing and uncertainty, according to STAT interviews with 11 staff members and researchers affiliated with the center. Read more from Jonathan and Jason.
nih
Overseas NIH grants are also in doubt
The NIH said last week that it will no longer let U.S. researchers give foreign collaborators funding to help with projects. It turns out that the new policy is far more sweeping than originally thought, Megan Molteni reports.
Privately, NIH leadership is making it clear that the moves are part of a broader America First agenda that seeks to dramatically reduce U.S. participation in international science.
Megan obtained an email from principal deputy director Matthew Memoli in which he says the NIH’s entire “foreign component” portfolio “needs to undergo review.”
Read more from Megan.
vaccines
NIH spends big on an old-fashioned technology for a universal flu vaccine
Even when NIH does commit money for a big project, scientists question whether it’s wise, Helen Branswell reports.
NIH is investing $500 million to develop a vaccine platform for pathogens that could trigger pandemics, but that research will use technology first developed decades ago.
“There is incredible work going on,” said a scientist familiar with the scope of research that is being done to try to develop a so-called universal flu vaccine. “This is not it.”
Read more from Helen.