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Radiopharma CDMO gets a new CEO in Stephen Hahn Read in browser
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20 August, 2025
GLOBAL PHARMA AND BIOTECH SUMMIT - Embracing and industry reset
Biopharma is grappling with diverging policies between the US, EU, and Asia — including proposed drug pricing reforms in the US and new EU regulations taking effect this year. The need for strategic clarity has never been more urgent. Join us in London — in person and virtually — where we’re bringing together the industry’s most influential voices to chart a path forward.
top stories
1. Hundreds of current and former HHS workers blame RFK Jr. for 'deliberate destruction' of trust
2. Nucleus RadioPharma taps former FDA commissioner as CEO 
3. Enanta files patent suit against Pfizer in Europe
4. Healthcare costs to go up 9% in 2026 for large employers
5. FDA lifts hold on Rocket’s pivotal study for its gene therapy, which is now a lower dose
6. With $42M, Jazz turns to Copenhagen biotech to build out epilepsy pipeline
7. XOMA buys third biotech this month, as it swoops up Mural Oncology
8. Catalent lays off 350 workers over change in demand from a ‘large customer’ 
9. American Academy of Pediatrics breaks with RFK Jr., CDC on Covid vaccines for kids
10. Celldex shelves antibody in swallowing disorder, looks to itching readouts next year
more stories
 
Jaimy Lee
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We’re about a month out from our annual Endpoints 11 event, which recognizes the industry’s most promising biotechs. You can register to watch the event or join us live in Boston on Sept. 26. See you there!

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Jaimy Lee
Deputy Editor, Endpoints News
HHS Secretary Robert F. Kennedy Jr. (Graeme Sloan/Sipa USA)(Sipa via AP Images)
1
by Max Bayer

More than 750 cur­rent and for­mer fed­er­al health work­ers are call­ing on HHS Sec­re­tary Robert F. Kennedy Jr. to change his tune in the wake of a dead­ly shoot­ing at the CDC’s head­quar­ters in At­lanta.

The let­ter, which was re­leased Wednes­day on a new site called Save HHS, de­scribed Kennedy as “com­plic­it in dis­man­tling Amer­i­ca’s pub­lic health in­fra­struc­ture and en­dan­ger­ing the na­tion’s health by re­peat­ed­ly spread­ing in­ac­cu­rate health in­for­ma­tion.” In a sep­a­rate press re­lease, Save HHS said he is “en­dan­ger­ing lives.”

Patrick Joseph White, who opened fire at the CD­C's cam­pus and died by a self-in­flict­ed gun­shot wound, thought the Covid-19 vac­cine he re­ceived had made him sick, ac­cord­ing to news re­ports.

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Stephen Hahn, new Nucleus RadioPharma CEO (Kevin Dietsch/Pool via AP Images)
2
by Anna Brown

For­mer FDA Com­mis­sion­er Stephen Hahn has been named CEO of ra­dio­phar­ma man­u­fac­tur­er Nu­cle­us Ra­dio­Phar­ma, with the goal of ex­pand­ing the CD­MO’s foot­print.

Hahn served as FDA com­mis­sion­er be­tween 2019 and 2021 be­fore mov­ing to the po­si­tion of CEO-part­ner of Flag­ship Pi­o­neer­ing and CEO of Har­bin­ger Health. Hahn has al­so served as the chief med­ical ex­ec­u­tive at the Uni­ver­si­ty of Texas MD An­der­son Can­cer Cen­ter in Hous­ton.

Dur­ing his first year as CEO, Hahn plans to get the com­pa­ny's on­ly fa­cil­i­ty GMP-ready, as well as ex­pand its R&D ser­vices. Over the next five years, Nu­cle­us is plan­ning to “dra­mat­i­cal­ly in­crease” its man­u­fac­tur­ing foot­print.

Build­ing fa­cil­i­ties clos­er to pa­tients is cru­cial for ra­dio­ther­a­pies. Their very short half-life makes them dif­fi­cult to trans­port over long dis­tances.

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2025'S BREAKOUT STARTUPS. WHO'S ON THE LIST? - Endpoints 11
Endpoints News returns to Boston’s State Room to announce the 2025 class of biotechs worth watching. Join the live unveiling and see the industry’s next chapter come into focus. Which biotechs will make the leap? Join us.
3
by Nicole DeFeudis

Enan­ta Phar­ma­ceu­ti­cals is es­ca­lat­ing its patent bat­tle over Pfiz­er’s Covid-19 an­tivi­ral Paxlovid.

The Wa­ter­town, MA-based drug­mak­er an­nounced Wednes­day that it filed suit against Pfiz­er in the Uni­fied Patent Court of the Eu­ro­pean Union. Enan­ta al­leges that Paxlovid in­fringes its ‘265 patent based on a 2020 ap­pli­ca­tion that de­scribes “coro­n­avirus pro­tease in­hibitors in­vent­ed by Enan­ta sci­en­tists.”

Pfiz­er beat a sim­i­lar chal­lenge brought by Enan­ta in fed­er­al court in Mass­a­chu­setts, but Enan­ta filed an ap­peal in Feb­ru­ary. In Eu­rope, Enan­ta ex­pects a hear­ing with­in the court’s 12-month tar­get, and a de­ci­sion “with­in weeks there­after," the com­pa­ny said in a news re­lease.

A Pfiz­er spokesper­son told End­points News on Wednes­day that the com­pa­ny is “con­fi­dent in our IP sur­round­ing Paxlovid and will re­spond in due course in court.”

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4
by Lydia Ramsey Pflanzer

Health­care costs are ex­pect­ed to in­crease more than they have in re­cent years, ac­cord­ing to a sur­vey of large em­ploy­ers.

The em­ploy­ers ex­pect health­care costs to in­crease by a me­di­an of 9% in 2026, up from 8% in 2025, ac­cord­ing to the Busi­ness Group on Health’s an­nu­al sur­vey of 121 large em­ploy­ers pro­vid­ing health cov­er­age to a to­tal of 11.6 mil­lion peo­ple. The sur­vey was con­duct­ed be­tween June and Ju­ly. Af­ter changes to plan de­signs, the in­crease is still ex­pect­ed to go up 7.6%.

Ex­pen­sive ther­a­pies, in­clud­ing GLP-1 med­ica­tions, are dri­ving that in­crease, ac­cord­ing to the sur­vey.

While the med­ica­tions have shown they’re clin­i­cal­ly ef­fec­tive, “they al­so con­tin­ue to as­tound and stress from a cost per­spec­tive,” Ellen Kel­say, the group’s CEO, said Tues­day on a press call. In 2026, 73% of em­ploy­ers sur­veyed said they in­tend to cov­er GLP-1s for obe­si­ty, up from 67% the year be­fore.

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