A study in the journal Annals of Oncology found that patients with metastatic castration-resistant prostate cancer had similar survival outcomes and fewer adverse events with Lu-177-PSMA-617, or Pluvicto, compared with switching to androgen receptor pathway inhibitors after progression. A study in the journal European Urology Oncology found that for patients with ARPI-mCRPC, continuing an ARPI with Pluvicto did not improve response rates or overall survival when compared with Pluvicto alone.

Researchers reported in the Journal of Translational Medicine that they developed a patient-derived organoids-based xenograft model for primary aldosteronism to improve preclinical research and imaging evaluations. The model, which maintained key pathological features, was assessed using PET/CT imaging with [18F]AlF-NOTA-pentixather.

PSMA PET/CT is more accurate than CT and bone scintigraphy in detecting advanced prostate cancer metastases, and PSMA radioligand therapy is effective for castration-resistant disease, according to a review in the journal Urologie. Researchers expect numerous studies in the coming years on the effectiveness of PSMA radioligand therapy in earlier stages of prostate cancer and in combination with other therapies.

Life Molecular Imaging has expanded production and distribution of Neuraceq, a florbetaben F-18 injection, in Southern California. The expansion is intended to improve access to the diagnostic agent, used for detecting brain amyloid plaques in patients with cognitive impairment.

A report from Kaufman Hall finds that US physicians and specialists are providing more services but seeing stagnant pay due to flat insurer reimbursements and inflation. Net revenue per full-time provider increased 5% from 2023 to 2025, but net revenue per unit of work decreased by 7%.

Close to two-thirds of US drug production facilities are in counties that have had hurricanes, wildfires or other disasters in the past six years, posing significant supply chain risks, according to a study in the Journal of the American Medical Association. Natural disasters have caused drug shortages in the past, and the findings highlight the importance of considering climate-related vulnerabilities in the supply chain, researchers wrote.

An ESR survey published in Insights into Imaging highlights the varied recognition of radiology subspecialization across Europe. Of the 37 countries surveyed, 12, including Austria and Italy, do not recognize subspecialties. The survey noted a range of zero to 12 recognized subspecialties across countries and identified potential areas for future recognition, such as nuclear medicine and cancer screening programs.

Advocacy by SNMMI resulted in the Senate Appropriations Committee including in its fiscal 2026 report for Labor, Health and Human Services a request that NIH's National Cancer Institute support research using theranostics. The committee also included in its fiscal 2026 Department of Defense report neuroendocrine tumors as an allowable research area in the Congressionally Directed Medical Research Program's Peer-Reviewed Cancer Research Program, which also was supported by SNMMI.