Research from JAMA Network Open highlights that adolescents and young adults with cancer experience higher anxiety and depression rates than older adults. The study emphasizes the urgent need for mental health interventions tailored to younger cancer patients, especially given the rising suicide rates in this group.

A research letter published in the journal Obstetrics & Gynecology found that people ages 18 to 50 with endometriosis had a 42% higher risk of self-harm, overdose or suicide, compared with a control group. The risk was particularly high among those with little or no history of psychiatric care.

Isotretinoin treatment for acne in adolescents was linked to slower growth rates but did not affect final adult height, compared with antibiotics, researchers reported in the Journal of the American Academy of Dermatology. The researchers said even with the study data, "the risk of a potential negative effect on growth should be carefully considered for each individual patient as part of shared decision making."

Clinical interpretive reports are helping NICU physicians use rapid genomic sequencing to improve care for newborns. The reports make genomic data more accessible, classifying variations and providing actionable information, according to a study in the journal Genetics in Medicine. "CIRs give them more accessible and actionable information, which they can then share with medical colleagues and families," said Dr. Pankaj Agrawal, chief of the University of Miami's Division of Neonatology.

Children living in areas with high social vulnerability have a higher risk of asthma-related emergency department visits when school starts, according to a study in The Journal of Allergy and Clinical Immunology. Factors such as crowded classrooms and limited access to health care exacerbate the risks.

A study in BJOG involving 634 pregnant women with polycystic ovary syndrome found that metformin use was associated with a reduced rate of maternal infections, particularly viral infections. However, children exposed to metformin in utero had a higher long-term risk of allergies and eczema.

A study in JAMA Network Open found that 32.5% of people surveyed reported using over-the-counter birth control pills, with a notable uptake among uninsured individuals, adolescents and those living in rural areas. The study, conducted about two years after the FDA's approval of the OTC pill Opill, found that 26.2% of users had not been using any modern birth control method before the OTC option.

A two-year, nurse-led phone intervention was associated with significant reductions in BMI in preschool children, especially those from lower-income families, according to a study in the International Journal of Obesity. The program, which included support calls and text messages, led to better dietary habits and less screen time.

Dr. Judy Aschner of Hackensack Meridian Health has received a $27 million NIH grant to advance research on the effects of environmental factors on children with disabilities. As part of the ECHO program, this study will examine prenatal and perinatal exposures and their impact on children with sensory, motor, and neurodevelopmental issues, and aims to uncover modifiable factors that can enhance health outcomes and life satisfaction for these children.

Watch Henry Winkler talk about himself as Fonzie doing a literal interpretation of the Hein idiom.

Danielle Jones is a health care editor at SmartBrief where she edits content about pediatrics, biotechnology and nuclear medicine. She's been a medical editor and writer for 15 years now and has a background in clinical practices. You can contact her by email with feedback and ideas. If you find this newsletter helpful, please share it with a friend or colleague who might like to subscribe. It's free!