October 15, 2025
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Morning Rounds Writer and Reporter
Good morning, and happy STAT Summit. Lots of exciting stuff going on, and lots of great outfits to be seen. Who's the best dressed STAT reporter at the Summit? Send nominations to theresa.gaffney@statnews.com 

politics

CDC workforce is down 33% since Trump’s start, per union

The union representing CDC employees estimated Tuesday that the Atlanta-based agency's workforce has been reduced by 33% since the Trump administration took office. That figure represents people who have been laid off in the three rounds (so far) of reduction-in-force notices, staffers let go because they were on probation or whose term contracts were not renewed, and employees enticed to take early retirement through the "Fork in the Road" offer.

More than 1,300 new layoff notices were issued Friday night, but about 700 of those workers were informed Saturday they'd been victims of a "coding error" and weren't losing their jobs after all. Yolanda Jacobs, president of local 2883 of the American Federation of Government Employees, isn't buying that explanation, calling the layoffs "a politically motivated stunt" during a press conference.

By the union's tally, about 3,000 people, or 23% of the CDC's workforce, has been fully separated from the agency so far this year. Another 1,300 employees who received RIF notices in April (700) and last weekend (600) are on administrative leave — being paid, but no longer able to do their jobs. Those who were let go last Friday will be terminated Dec. 8. — Helen Branswell 


more politics

The people behind CDC’s top health survey are gone

As Helen wrote, more than half of the terminations brought down on the CDC late last week have since been rescinded. But one team has not seen any reprieve: the National Center for Health Statistics, which directs a critical annual survey on health and nutrition. The office lost about 100 people in the latest layoffs, including all eight employees left in the planning branch after the first round of cuts last spring. 

The loss puts at risk information about health services, hospitalization, ER visits, office visits, and individual warning signs of disease. “The [reductions in force] may have left some parts of NCHS intact, but a car cannot drive missing a tire or the steering wheel,” said Denys Lau, who formerly directed a division within NCHS that tracks the nation’s health care provision and utilization. Read more from STAT’s Liz Cooney, who spoke with insiders all weekend to keep us up to date on the latest chaos.  


irl

What to look forward to at day one of the STAT Summit

Today’s the day! We’ve got a packed agenda ahead — here’s what to look out for:

  • At 6 months old, KJ Muldoon received a gene-editing treatment custom-built to correct his unique mutation. Researchers in the field have both optimistic and pessimistic takeaways from the experience. This morning, STAT’s Jason Mast will moderate a panel including KJ’s family and key researchers behind the treatment, focused on what they accomplished and what it could mean for medicine. And as an adorable treat: Baby KJ (who is now more than a year old!) will also be in attendance.
  • As you’ve been reading in this newsletter, the CDC is struggling. STAT’s Daniel Payne will speak with former CDC leaders about the pace of the changes, the implications, and the view from inside the agency.
  • Today we’re announcing the 2025 STAT Wunderkinds — a class of early-career researchers, doctors, and overall scientific superstars. Learn about them all here, and this afternoon STAT’s Katherine MacPhail will talk with a few honorees, including a researcher who focused on coronaviruses before the pandemic, a CRISPR scientist who brainstorms while training for ultramarathons, and a pediatric resident who is also starting a biotech company.


biotech

How this southern state became a go-to destination for biotech

FUJIFILM Biotechnologies

The former plantation town of Holly Springs — once dubbed the “poverty pocket” of its wealthy North Carolina county — used to be something of a wasteland, according to former acting FDA commissioner Ned Sharpless, who began his medical career in the state. But now? Genentech is spending $700 million to build there; Amgen has pledged $1.5 billion to construct a manufacturing plant; and pharmaceutical contractor FUJIFILM Diosynth is in the midst of a $3 billion project that will create 1,400 jobs.

“[It] seems like every day I hear of another large pharma company building a $2 billion plant down here,” Sharpless told STAT’s Allison DeAngelis. Read Allison’s great story about how North Carolina built manufacturing boomtowns for biotech at a time when most other companies in the field are grappling with layoffs, a lack of financing, and federal pressure.


first opinion

How many Medicare plan choices is too many?

Nearly 7 in 10 Medicare beneficiaries did not compare plans when selecting their 2022 coverage, according to a KFF survey. Among those with stand-alone prescription drug plans, half did not compare options for 2024 coverage, per another study from the USC Schaeffer Institute. So maybe there are already too many options  — and too few resources to help older Americans choose the best health care plan for them. That’s the argument made by two public policy experts in a new First Opinion essay. 

“Policymakers could do much more to simplify beneficiaries’ plan choices — after all, that’s what beneficiaries want,” the two authors write. Read more on what might ease the pressure.


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What we're reading

  • What’s the deal with weighted vests? The 19th

  • Listen: Former acting CDC director on public health changes: ‘absolutely heartbreaking,’ STAT
  • Scientists identify key reason people may use or get addicted to cannabis, Washington Post
  • German biotech Tubulis raises $356 million to advance cancer treatments, STAT

Thanks for reading! More next time,