A study using two tumor models found that for breast and colon cancer, low-dose, fractionated image-guided radiation therapy was linked to better antibody tumor penetration, compared with single-dose IGRT, researchers reported in The Journal of Nuclear Medicine. IGRT used with low-dose targeted alpha therapy was better for tumor regression and survival. In the colon cancer model, triple therapy with fractionated IGRT, low-dose TAT and immunocytokine therapy was linked to complete cures in most mice and rechallenge rejection.

In addition to already approved tracers, numerous Ga-68 radiopharmaceuticals and theranostic pairs are currently under investigation for use across a wide range of disease states and cancers. Learn more about the benefits of this isotope at gallium68.com

www.gallium68.com

A Phase II trial presented at the European Society of Medical Oncology's annual meeting is evaluating the efficacy of Lu-177-PSMA-617 in treating metastatic clear cell renal cell carcinoma. PSMA is overexpressed in the tumor vasculature of clear cell renal cell carcinoma, according to researcher Dr. Emmanuel Seront.

A Novotech white paper detailed a 10-fold increase in therapeutic radiopharmaceutical trials globally since 2018, with more than 80 active studies as of August 2025. "Radiopharmaceuticals represent one of the most exciting and transformative advancements in oncology, but success depends on precise execution across clinical, regulatory, and supply-chain dimensions," said Novotech's Courtney Thornley.

GE HealthCare reported a 6% increase in revenues to $5.1 billion in the third quarter of 2025, driven by its Imaging, Advanced Visualization Solutions and Pharmaceutical Diagnostics segments. Imaging revenue rose 5% to $2.3 billion. The company highlighted a deal with CDL Nuclear Technologies Group to distribute Flyrcado in the US and a licensing agreement to develop, manufacture and commercialize F-18 piflufolastat in Japan.

A study in the Journal of the American College of Radiology found an increase in subspecialization among radiologists following practice closures. The share of radiologists practicing as subspecialists rose by 2.5 percentage points after a closure, compared with 1.8 percentage points for those whose practices remained open. "Growing subspecialization in medicine has the benefit of advanced expertise for complex care, but it can also cause access challenges for care across more common clinical needs," said study co-author Elizabeth Rula.

The Korea Atomic Energy Research Institute and the University of Missouri have signed a new agreement to expand collaborative research and personnel exchanges. The agreement establishes a framework to deepen collaboration in six areas: radioisotopes, reactor technology, advanced reactor instrumentation, materials science, neutron research and advanced computing. The deal builds on their long-standing ties and also supports the university's plan for a next-generation research reactor.

A federal judge has indefinitely blocked the Trump administration's plan to lay off more than 4,000 federal employees during the government shutdown. US District Judge Susan Illston sided with unions, stating the layoffs likely overstep executive authority. The administration had indicated that more than 10,000 employees could eventually be laid off.

The FDA is still operational during the government shutdown by using leftover user fees from 2025, allowing about 85% of the agency to function. However, delays are emerging, affecting programs like the Small Business Innovation Research initiative and potentially impacting biopharma companies.

Share your research. We're inviting you to submit an original clinical or scientific abstract to present at the 2026 SNMMI Annual Meeting -- May 30 to June 2 in Los Angeles. This is your opportunity to showcase your work to leading professionals in nuclear medicine and molecular imaging. Submission Deadlines: Jan. 6, 2026 (General) and Feb. 6, 2026 (Technologist Students)