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Endpoints News
Thursday, 4 December 2025
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A year of scrutiny for health insurers
A year ago, we started our day chasing down the shocking news that UnitedHealthcare CEO Brian Thompson had been shot and killed outside a Midtown Manhattan hotel.
The news, and especially the following online fury at the health insurance industry, seemed like a big moment. At the time, we wrote that “the reaction expressed a deep frustration with the healthcare system — and it would be a mistake for the healthcare industry to ignore that. There’s no time more vulnerable than when you need medical care, and in that moment, you just want your healthcare benefits to work. It’s clear that’s not often people’s experiences.”
We asked a handful of trusted sources whether anything has changed, either for the industry or the public. (We also reached out to UnitedHealthcare, which declined to comment.) 
Warris Bokhari, CEO of Claimable, a startup that uses AI to help people appeal insurance denials, said that if anything, things are worse. That’s in part because of how the health insurance industry has fared over the last year. Medical costs are cutting into insurers’ businesses, and over the last two years, organizations like CVS Health and UnitedHealth have changed CEOs. Pressure is coming not just from consumers, but investors as well. 
We’re in a situation where these insurers are defending the indefensible. The question to me is, at what cost?” Bokhari said.  
Healthcare consultant and insurance expert Ari Gottlieb said that nothing has fundamentally changed. Sure, insurance companies can be frustrating, but they don't mean to be destructive. The steps companies have taken have been minor, like eliminating some pre-authorization requirements, which some states have already gotten rid of.
Instead, the biggest challenge insurers will face this year is the federal funding pullback from Medicaid and the ACA marketplace. He expects little will change going forward.
“As much as hospitals complain about insurers, they prefer this model because they know how to make it work for them,” he said. "It's a lot of talk around the edges, but they've all figured out how to optimize it.”
Luigi Mangione, accused of killing Thompson, is currently awaiting trial and undergoing a pretrial hearing. He's pleaded not guilty. As the case gets underway, we’ll be watching to see how much of that initial frustration around the healthcare industry — if any — sticks around.
- Lydia and Ngai
Here’s what’s new
Home care startup Inbound Health shuts down
It’s the latest in a string of health tech closures, as investors who once wrote checks freely have grown more cautious, and as the fate of pandemic-era regulatory permissions is left unclear.
Clinical trials tech startup Paradigm raises $78M, acquires part of Roche’s Flatiron
When Ken Fra­zier led Mer­ck, one of the chal­lenges of de­vel­op­ing Keytru­da was get­ting the block­buster-to-be im­munother­a­py to a broad set of pa­tients. Many pa­tients who could have ben­e­fit­ed from the drug could­n't ac­cess it in the cur­rent tri­al sys­tem.

Frazier, who retired from Merck in 2021, is now on the board of Paradigm Health, a startup aiming to fix those problems that has just raised a $78 million Series B round. Alongside Thursday’s financing, Paradigm also said it acquired the clinical research business of Roche-owned Flatiron Health for undisclosed terms.
9-figure rounds
22

The number of health tech funding rounds that were above $100 million this year, totaling $5.9 million in funding by mid-November, according to a new report from PitchBook. 

This week in health Тech
Hims & Hers is building onto its lab-testing business by acquiring YourBio Health, a Flagship-backed startup that developed a blood sampling device using micro-needles. The deal is expected to close in early 2026. It’s the second testing-related acquisition Hims has made, after it bought at-home lab testing company Trybe Labs earlier this year.
Two employer-focused health insurance startups raised significant funding in their respective Series B funding rounds. Curative raised $150 million for its no-copay, no-deductible approach to insurance (as long as members complete a preventive visit), while Angle Health raised $134 million for its AI approach to insurance.

Artera, a startup using agentic AI for patient communications, raised $65 million. Lead Edge Capital led the growth investment. 

Minnesota-based Medicaid startup Reema Health raised $19 million.  LRVHealth and Optum Ventures backed the Series B round.
Joi + Blokes, a telehealth company for women with a focus on longevity, has acquired fellow women’s virtual care startup HerMD.
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