Pediatrics Today SmartBrief
PECARN rule may help assess infants for bacterial infections
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December 11, 2025
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Adolescents with migraines face higher hypertension risk
 
Girl has a cold. Health issues. Coronavirus covid problem, self isolation at home. Melancholy and depression. Conceptual of bad condition of broken hearted, sadness, loneliness or depress woman.
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A study published in the journal Hypertension found that adolescents with migraines may be at a higher risk of hypertension. The study, which included more than 2 million young patients in Israel, found that those with migraines had a much higher risk of hypertension compared to those without, and the association was stronger among those with severe migraines. The study suggests that identifying migraines as a hypertension risk marker could lead to earlier detection and prevention.
Full Story: Sleep Wake Advisor (12/3)
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Childhood, young adult overweight raises later CHD risk
Being overweight as a child and young adult was linked to a greater likelihood of coronary heart disease in adulthood, but normalizing weight before young adulthood may help reduce the risk, researchers reported in JAMA Pediatrics. The study followed 103,232 people born between 1945 and 1968 for an average of 37.8 years. Overweight as a young adult was associated with a higher risk than overweight as a child, and people who normalized their weight before young adulthood had a CHD risk as adults similar to peers who had maintained a normal weight.
Full Story: Medscape (12/10)
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Pediatric Health Care
 
Study: What may cause rare myocarditis risk with COVID-19 vaccines
A study in the journal Science Translational Medicine found that the molecules CXCL10 and interferon-gamma were present at higher levels in the blood of people who developed myocarditis after receiving a COVID-19 vaccine. The researchers found that using antibodies to block the molecules reduced cardiac stress in mice that received the vaccine.
Full Story: STAT (12/10)
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Study finds inhaled insulin safe for youth with T1D
A study in the journal Diabetes Care found that inhaled Technosphere insulin was safe for children and adolescents with type 1 diabetes, and associated with greater satisfaction and less weight gain when compared with rapid-acting insulin. However, it did not meet noninferiority criteria for HbA1c outcomes.
Full Story: Medscape (12/10)
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AACR report highlights gains, gaps in pediatric cancer
The American Association for Cancer Research's first Pediatric Cancer Progress Report highlights advancements in molecular diagnostics, targeted therapies and immunotherapies, resulting in an overall five-year survival rate exceeding 85%. However, survival rates for aggressive brain tumors and rare solid tumors have seen little improvement in over 40 years, and global disparities in access to care persist.
Full Story: Medscape (12/10)
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Leukemia treatment can create financial strain for families
 
Leukemia treatment can create financial strain for families
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A study presented at a meeting of the American Society of Hematology found that almost one-third of families experienced financial difficulties when their child had chemotherapy for pediatric acute lymphoblastic leukemia. The study, which involved 422 families in the US and Canada, found that by the end of two years of treatment, 30% of families struggled with living expenses and 32% had lost a quarter or more of their annual income.
Full Story: HealthDay News (12/11)
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The first 6 months are critical.
This 30-second, 4-position motor exam is simple, fast, and incredibly effective at picking up on atypical motor patterns, often before they become visible to caregivers. Earn CME, learn the exam, and start spotting delays early. Identify Patterns Early.
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Trends & Technology
 
PECARN rule may help assess infants for bacterial infections
A study in the Journal of the American Medical Association found that the Pediatric Emergency Care Applied Research Network clinical prediction rule had a sensitivity of 94.2% and a specificity of 41.6% in identifying invasive bacterial infections in febrile infants 28 days or younger who did not appear to have an illness. The rule found 41.1% of infants were low risk, potentially reducing the need for lumbar punctures, hospitalizations and antibiotic use.
Full Story: MedPage Today (free registration) (12/10)
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Playing sports may help reduce behavioral issues in boys
 
Playing sports may help reduce behavioral issues in boys
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A study in the European Child Adolescent Psychiatry found that boys ages 6 to 10 who consistently participated in organized sports had fewer symptoms of oppositional-defiant disorder at ages 10 and 12. "Sport may serve as a natural and influential context for learning self-regulation, cooperation and respect for rules," said lead researcher Matteo Privitera.
Full Story: HealthDay News (12/9)
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Health Policy & Regulations
 
US suicide rate declined in 2024
Preliminary data from the CDC show the US suicide rate decreased in 2024, falling to 13.7 per 100,000 people, from some of the highest levels previously recorded. Experts are unsure if this trend will continue, citing factors such as depression, limited mental health services and firearm availability. The rate dropped among people in their late 20s and early 30s, as well as in some Southern and Midwestern states. The Department of Veterans Affairs' screening programs and the 988 crisis line may have contributed to the decline in suicide, which is the nation's 10th leading cause of death.
Full Story: The Associated Press (12/10)
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Health care groups call for withdrawal of HIPAA update
More than 100 hospitals and health care associations have called on HHS to withdraw proposed updates to the HIPAA Security Rule, saying the changes would impose significant financial burdens on regulated entities with an impractical implementation timeline. The groups urged the HHS to collaborate on developing practical cybersecurity standards without imposing excessive regulatory burdens.
Full Story: HIPAA Journal (12/9)
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SmartBreak: Question of the Day
 
King Solomon's mines are said to be in Ophir. Christopher Columbus thought he found it when he landed where?
Oddly interesting: This archived New York Times article points to Peru as the source of Solomon's gold.
VoteAmerican continent
VoteBelize
VoteCuba
VoteDominican Republic
 
 
 
 
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