CV Quality SmartBrief
Survival up, infections down at US hospitals | IV iron may cut mortality in anemia with bacterial infections | AI model targets care gaps in congenital heart disease
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December 11, 2025
 
 
CV Quality SmartBrief
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First Focus
 
Survival up, infections down at US hospitals
 
Doctor walking down hospital corridor.
(Science Photo Library/Getty Images)
A new American Hospital Association report based on data from Vizient shows that survival rates in US hospitals have increased 30% since 2019, central line-associated bloodstream infections have decreased 24%, and urinary tract infections linked to catheters decreased 25%, as of mid-2025. Breast and colon cancer screenings increased 95% over the study period, according to the report.
Full Story: Healthcare Innovation (12/8)
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IV iron may cut mortality in anemia with bacterial infections
IV iron infusions were associated with improved survival and hemoglobin levels in patients with anemia and acute bacterial infections, according to a study of more than 85,000 patients that was presented at the American Society of Hematology annual meeting. Benefits were seen in all groups except those with meningitis, and the biggest mortality decreases were in patients with methicillin-resistant Staphylococcus aureus bacteremia and pneumonia. 
Full Story: Managed Healthcare Executive (12/6)
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AI model targets care gaps in congenital heart disease
Researchers have developed an AI model to identify patients with congenital heart disease who are at risk of experiencing gaps in continuous care, as presented at the American Heart Association Scientific Sessions. The model, which utilizes data from 1,746 patients, takes into account factors such as social determinants of health and disease complexity. While the model shows strong performance in identifying patients maintaining follow-up, it needs refinement to better predict those with care gaps.
Full Story: Healio (free registration)/Cardiology today (12/8)
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Practice & Hospital Management
 
Physician shortages are narrowing care access
The US physician shortage is expected to reach 86,000 by 2036, according to Association of American Medical Colleges data. Shortages make it difficult for many residents to access care, and they are driven by a growing and aging population, physician retirements and other factors. Efforts to address the issue include expanding medical school class sizes, increasing residency programs and using telemedicine, but challenges persist including medical education costs and federal funding limitations.
Full Story: Greenville Business Magazine (S.C.) (12/8)
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Dual scoring improves heart risk assessment in COPD
Research published in the journal Chest indicates that using the cardiovascular risk score and coronary artery calcium score together improves the prediction of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease. The study, involving 549 patients, showed that those with high scores in both metrics had a significantly increased risk of MACE. While the combined scores offer a promising tool for clinical settings, the study's limitations include its focus on a low-risk region, and a predominantly male cohort.
Full Story: Medscape (12/8)
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Innovation & Technology Trends
 
AI-designed antibodies poised to advance drug development
Scientists are making strides in using artificial intelligence to design antibodies, with the potential to advance therapeutic development. Recent efforts have led to the creation of nanobodies and full-length antibodies with properties similar to commercial drugs. Key players in this field include Nabla Bio, Chai Discovery and the University of Washington. While initial AI-designed antibodies lacked potency, new tools have improved their design, targeting diseases like cancer and infections.
Full Story: Nature (12/9)
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Donate to the ACC Foundation + Make a Difference
Give a gift that will fund scientific research, provide young people with pathways to careers in cardiology and help us distribute education to clinicians in underserved communities. You can help us transform the future of cardiology and ensure every patient has access to quality care.
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Health Equity & Prevention
 
Socially vulnerable communities lack cardiac rehab access
Rural areas experience notably worse access to cardiac rehabilitation facilities compared with metropolitan counties, according to a study in the Journal of the American Heart Association. The research showed that among all US counties, the median distance to the nearest county with a CR facility was more than 16 miles.
Full Story: Cardiology Advisor (12/9)
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Groups partner to advance interventional cardiology
 
Mature surgeon explaining colleagues during meeting. Female doctor is gesturing while talking with coworkers. They are sitting at conference table in hospital.
(Morsa Images/Getty Images)
The Society for Cardiovascular Angiography and Interventions and Cardiovascular Research Technologies have formed a collaboration to advance the field of interventional cardiology through education, advocacy and research. The partnership will include discounted registration for SCAI members at CRT 2026, a Day on the Hill event and joint efforts in developing clinical trials and data registries.
Full Story: Cardiovascular Business (12/3)
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