Publicly accessible DNA research is a prime target for hackers, according to researchers.
The vulnerabilities present risks to the privacy of individuals, scientific integrity and national security, they said.
So-called next-generation DNA sequencing - the fast, modern way to determine the sequence of chemicals in a DNA molecule - lets researchers analyze large amounts of genetic material and discover variations associated with diseases, drug treatments and other biological phenomena.
But the highly specialized instruments, technologies and software have multiple points of vulnerability, the researchers reported in IEEE Access after reviewing previously published studies. And because many DNA datasets are openly accessible online, there are many possible ways for cybercriminals to access and misuse the information for surveillance, manipulation or malicious experimentation, they said.
Among the weaknesses, for example: biochips used with DNA sequencers are susceptible to malware attacks, including trojans that can masquerade as legitimate software, the researchers said. An infected microchip can leak sensitive sequencing data or manipulate genetic information, introducing inaccuracies in crucial genetic data essential for medical diagnostics and research, they added.
Another example: attackers could analyze regions of DNA that have been "amplified" - that is, when many copies of that region have been created for research purposes - and find ways to match those regions against public genealogy databases to infer personal information associated with the DNA profiles, linking DNA samples back to individuals, the researchers said.
"Despite its importance, cyber-biosecurity remains one of the most neglected and poorly understood research disciplines and is leaving a critical gap in global biosecurity," study leader Dr. Nasreen Anjum of the University of Portsmouth's School of Computing said in a statement.
"To make sure our DNA information stays safe and is used only for good, we're urging more research and collaboration to find ways to keep this powerful technology secure."