A study published in Epic Research reveals that 25.1% of patients with elevated low-density lipoprotein cholesterol have no documented use of statin therapy. The study analyzed records of 763,498 patients from the Epic Cosmos dataset, showing that young adults ages 18 to 39 are the most likely to lack documentation for lipid-lowering medications.

Whole-genome sequencing is gaining traction as a more comprehensive diagnostic tool for rare diseases, capturing abnormalities in both coding and noncoding regions of the genome. The technique has become more accessible, costing less than $1,000, and is being used more frequently in the US and Europe, although reimbursement remains a challenge in the US.

AI and analytics have emerged as the top health care IT investment priorities globally in 2025, followed by electronic health records and IT infrastructure, according to a KLAS Research report. The study highlights rapid cloud adoption to support AI and modernization efforts, with Microsoft Azure, AWS and Google Cloud as leading providers. Consulting firms, Deloitte, EY, KPMG and PwC, are increasingly guiding these transformations.

Forty-eight House Democrats have sent a letter to the Office of Management and Budget demanding the Department of Government Efficiency stop unauthorized use of artificial intelligence, particularly in handling sensitive data. The letter, led by Reps. Don Beyer, Mike Levin and Melanie Stansbury, cites data privacy and cybersecurity risks, and asks whether DOGE has used AI for decisions about federal employment or contracting.

UChicago Medicine is leveraging artificial intelligence through its Center for Digital Transformation to enhance patient care and operational efficiency, with Chief Medical Information Officer Dr. Cheng-Kai Kao leading efforts to ensure AI accuracy and manage cybersecurity risks. The hospital is also focused on digital equity, helping patients access necessary devices and addressing potential biases in AI.

A study in NEJM AI suggests that an artificial intelligence-based algorithm could help detect liver disease using standard echocardiography images. The algorithm was developed using 1.5 million echocardiogram videos and was able to identify cirrhosis and steatotic liver disease, with higher accuracy for cirrhosis.

Interleukin-17A inhibitors, especially secukinumab, are associated with a higher risk of inflammatory bowel disease in patients with psoriasis or ankylosing spondylitis compared with apremilast, according to a retrospective study published in Alimentary Pharmacology and Therapeutics. The study, which analyzed data from 26,432 patients, notes an increased incidence of Crohn's disease and ulcerative colitis, particularly among those older than 60.

A study in Scientific Reports highlights a correlation between the monocyte-to-HDL-C ratio and gout risk and severity of renal dysfunction. The research, using data from the National Health and Nutrition Examination Survey, notes the link is particularly strong in males, Mexican Americans, married individuals, those with insufficient physical activity and those with diabetes.

A study by Avenir Health estimates that 25 million people could die over the next 15 years if the US eliminates its $12 billion annual global health funding. The Trump administration has already cut billions, affecting programs for HIV, tuberculosis and maternal health. The study, which uses robust mathematical models, highlights the potential for 15 million additional AIDS deaths and 2 million more tuberculosis deaths without US support.

A study highlights racial disparities in health care utilization among patients with inflammatory bowel disease, finding that Asian and Hispanic Americans use less health care than white Americans, while Black Americans 65 and older have higher emergency department visits. The research, published in the American Journal of Gastroenterology, suggests socioeconomic factors contribute to these disparities.