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Thursday
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13 November, 2025 |
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Novartis opened a new factory in Carlsbad, CA, on Monday to make its radioligand therapies. The factory is Novartis' third facility in the US, and will make Pluvicto and Lutathera. Stay tuned as we keep a close eye on how radiopharma drugmakers continue to boost their production footprints. |
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Anna Brown |
Biopharma Breaking News Reporter, Endpoints News
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2025 Convention on Pharmaceutical Ingredients confab in Frankfurt. (Credit: Anna Brown) |
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by Anna Brown
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As the White House continues to roll out “most favored nation” deals with drugmakers, contract manufacturing execs don’t anticipate any pricing pressure to impact their businesses — for now. Endpoints News spoke with executives from manufacturers, including Thermo Fisher, Fujifilm, Recipharm
and Siegfried, on the sidelines of the Convention on Pharmaceutical Ingredients confab in Frankfurt. They all said they’ve seen no impact yet from President Donald Trump’s push to bring US drug prices in line with cheaper rates paid abroad. “ is entirely on the pharma companies that have to manage those pricing aspects,” said Anil Kane, Thermo Fisher’s global head of technical and scientific affairs. | |
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WuXi AppTec US/EU President Richard Connell at the Financial Times' 2025 Global Pharma and Biotech Summit (courtesy Financial Times) |
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by Anna Brown
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LONDON — WuXi AppTec is creating its first European headquarters at its existing facility in Germany, the company’s US and EU president Rick Connell said Wednesday. “The time is right now to put the flag down and say, we're here. We're here to stay,” Connell said during the Financial Times’ Global Pharma and
Biotech Summit in London. The new headquarters will be located at the company’s site in Munich, which is home to its drug discovery service subsidiary called Crelux. WuXi AppTec also has a second European site in Couvet, Switzerland, which provides services in oral solid dose manufacturing. “While we have big operations in Asia and big operations in the US, we've
only had these two sites in Europe, yet we have several hundred customers here in Europe,” Connell added. | |
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by Anna Brown
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Abeona Therapeutics said the commercial rollout of its rare skin disease cell therapy has hit a roadbump, delaying the treatment of its first patient by several months. Although the company noted on Wednesday morning that there is high patient demand for its product, causing its stock ABEO to rally by as much as 18% at market close that day. Zevaskyn, approved in April, has a $3.1 million price tag and is among the most expensive therapies worldwide. Zevaskyn is for children and adults with recessive dystrophic epidermolysis bullosa, a rare, genetic skin disease in which patients are sensitive to blisters and wounds. After a biopsy of
the patient's own skin cells, sheets of skin with functional versions of collagen are made and then applied to the patient during surgery. | |
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Merck KGaA CEO Belén Garijo (L) and CFO Helene von Roeder (Arne Dedert/picture alliance via Getty Images) |
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by Anna Brown
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Merck KGaA is still in negotiations with the White House to determine how much its drug products will be exempt from President Donald Trump’s upcoming pharmaceutical tariffs, CFO Helene von Roeder said. "It's a little bit early to give you exact guidance on how we're looking at it,” von Roeder said during its third-quarter earnings call with
the media on Thursday. The company’s North American arm EMD Serono announced the deal in a splashy event at the White House last month. It agreed to lower prices of its IVF treatments and use "most favored nation" pricing for future drugs, in exchange for its products and ingredients to be exempt from the Department of Commerce's Section 232 pharma investigation. | |
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by Anna Brown
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Catalent will let go of more gene therapy staff in Maryland over continued issues in demand from a "large commercial customer," a company spokesperson told Endpoints News. A total of 77 workers will be laid off in the state, including 14 employees from Catalent’s gene therapy factory in Baltimore at the University of Maryland
BioPark, according to a WARN notice published on Nov. 6. The layoffs will take effect Jan. 5. In August, Catalent cut its headcount by 350 workers at the Baltimore factory over an "unexpected shift in demand" from an unknown customer. Catalent declined to name the company in
question, but one of its large customers there is Sarepta Therapeutics. Sarepta has faced a recent drop in demand for its Duchenne gene therapy Elevidys due to disclosures of patient deaths and paused shipments. | |
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by Ayisha Sharma
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LONDON — China’s biotech sector is steadily moving beyond a “me-too” approach to drug development thanks to a surge in quality talent, regulatory flexibility and |
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