Pam Bondi thought she understood the assignment. Donald Trump’s attorney-general prosecuted his enemies, insulted Democrats and fawned over the boss. But she mishandled the Jeffrey Epstein document-dump (by everyone’s lights), and most of her politicised prosecutions have flopped. So she is out of a job. Loyalty, while necessary in Trumpworld, is never sufficient.

And a new class of vaccines target not a single pathogen in the body, but lots of them. It is early days, with results in mice that may or may not translate to humans (or survive America’s disordered vaccine politics). But research into “everything vaccines” provides a bit of hope for readers (I imagine this includes you) who could use some this Easter weekend.

Finally, if you’ve been reading us all week, try our pint-sized news quiz and see if you know your Indian blockbusters from your Iranian islands.