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Hello Nature readers, |
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| Mice that received the RNA treatments rather than saline lived for about 4.5 months longer, on average. (Paul Chinn/The San Francisco Chronicle via Getty) | |||||||||||||||||
RNA molecule rejuvenates ageing miceInjecting old mice with an RNA molecule called miR-302b seems to reverse some signs of ageing — helping them to live longer, regrow hair and maintain their physical and mental abilities. The treatment works by targeting one of the hallmarks of the ageing process: a stage called cellular senescence, in which cells lose their ability to replicate. Researchers hope the findings could one day lead to the development of anti-ageing drugs, but more work is needed to determine whether they translate to people. Nature | 4 min readReference: Cell Metabolism paper |
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Pig-organ problem flipped to attack cancerScientists have disguised tumours to ‘look’ similar to pig organs ― tricking the immune system into attacking the cancerous cells. The team caused tumour cells to develop a feature found in transplanted pig organs: sugars on the surface of cells that provoke a fierce antibody attack. This ruse can halt a tumour’s growth and even eliminate it altogether, data from monkeys and humans suggest. But scientists say that further testing is needed before the technique’s true efficacy becomes clear. Nature | 5 min read |
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How to welcome academics fleeing warSocial scientist Tetyana Lunyova travelled more than 1,000 kilometres through Ukraine to flee the Russian invasion with her 10-year-old son. If they were separated, she told him, seek out an academic — they could help to track her down. Ultimately, Lunyova’s academic connections did prove crucial: she was able to take up a fellowship at a UK university with the help of the Council for At-Risk Academics (CARA), a non-governmental organization that supports academics facing threats or danger. Now, says CARA, the majority of people requesting help are from the Middle East. “The Ukraine experience shows what can happen when funding, supportive policy environments and collaborative approaches come together,” says CARA’s Zeid Al-Bayaty. Nature | 8 min read |
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The kissing problemPicture a coin on a table, surrounded by a ring of similar coins, pressed together as tightly as possible. The ring can fit six coins at most — this is known as its ‘kissing’ number, named after the ‘kiss’ between two billiard balls. In three dimensions — useful for packing a box of tennis balls, say — the number is 12. And in higher dimensions, things get really fun: a new proof has thrown tradition out the window to understand more about the sphere-packing conundrum. Quanta | 9 min read |
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| Oceanographer Andrea Kealoha set up sampling stations in the waters surrounding the Hawaiian island of Maui to monitor the impact of a 2023 wildfire on the neighbouring coral reefs. “The cage holds a sophisticated electronic sensor that measures the water’s temperature, salinity and pressure, as well as its oxygen, pH and chlorophyll levels and turbidity, or clarity, every 10 seconds for months and months,” she says. “Our community and our culture are so heavily connected to the ocean. We really need our ocean to be healthy, to support our community and our culture — and our economy, as well.” (Nature | 3 min read) (Nani Welch Keliihoomalu for Nature) | |||||||||||||||||
Quote of the day“Until we acknowledge that publish or perish is the natural consequence of the rankings obsession, we’re not going to fix anything.”Ivan Oransky, co-founder of the Retraction Watch website, responds to a survey of more than 1,600 authors of biomedical papers. Nearly three-quarters said there is a reproducibility crisis in science — and the leading cause is the “pressure to publish”. (Nature | 4 min read) |
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